研究成果： |
目前，杨照罡博士共发表SCI论文130余篇，其中以第一/责任作者身份发表SCI论文60余篇，代表性论文发表在Nature Biomedical Engineering，Nature Nanotechnology, Nature Communications, Advanced Materials，Journal of Controlled Release等高水平期刊上，总影响因子大于800，总被引频次7000余次，h因子为50，连续几年入选全球前2%顶尖科学家—年度科学影响力排行榜榜单。主持或参加美国NIH Research Project Grant Program (R21)等科研项目10项；授权/申请专利6项。以章节负责人及章节主要参与人身份参与撰写英文著作8篇。目前担任中国抗癌协会专业委员会委员，Asian Journal of Pharmaceutical Sciences 等期刊青年编委。此外，担任Biomaterials, Advanced Functional Materials, Journal of Controlled Release, ACS Nano等几十个期刊审稿人；以客座编辑身份在Frontiers in Pharmacology，Molecules，Frontiers in Immunology等多个SCI杂志组织发表特刊。 代表性论文： 1. K. Tang, Z. Tang, M. Niu, Z. Kuang, W. Xue, X. Wang, X. Liu, Y. Yu, S. Jeong, Y. Ma, A. Wu, B. Kim, W. Jiang*, Z. Yang*, C. Li*. Allosteric targeted drug delivery for enhanced blood-brain barrier penetration via mimicking transmembrane domain interactions, Nature Communications, 2025,16:3410（*通讯，影响因子14.7） 2. F. Gao, X. Liu, Z. Ma, M. Tang, Z. Tang, J. Wu, M. Luo, Y. Tang, X. Wang, B. Wang, B. Kim, Z. Yang*, W. Jiang*, P. Tang*, C. Li*. An integrated modular vaccination system for spatiotemporally separated perioperative cancer immunotherapy. Advanced Materials, 2025, e2418322（*通讯，影响因子27.4） 3. J. Chen, S. Hu, J. Liu, H. Jiang, S. Wang*, Z. Yang*. Exosomes: a double-edged sword in cancer immunotherapy. MedComm, 2025, 6(3): e70095（*通讯，影响因子10.7） 4. X. Bian, L. Yang, D. Jiang, A. Grippin, Y. Ma, S. Wu, L. Wu, X. Wang, Z. Tang, K. Tang, W. Pa, S. Dong, B. Kim, W. Jiang*, Z. Yang*, C. Li*. Regulation of cerebral blood flow boosts precise brain targeting of vinpocetine-derived ionizable-lipidoid nanoparticles. Nature Communications, 2024, 15(1):3987.（*通讯，影响因子14.7） 5. H. Zhang, A. Grippin, M. Sun, Y. Ma, B. YS Kim, L. Teng, W. Jiang*, Z. Yang*. New avenues for cancer immunotherapy: Cell-mediated drug delivery systems. Journal of Controlled Release, 2024, 375: 712-32. （*通讯，影响因子10.5） 6. S. Dong, X. Liu, Y. Bi, Y. Wang, A. Antony, D. Lee, K. Huntoon, S. Jeong, Y. Ma, X. Li, W. Deng, B. Schrank, A. Grippin, J. Ha, M. Kang, M. Chang, Y. Zhao, R. Sun, X. Sun, J. Yang, J. Chen, S. Tang, L. Lee, A. Lee, L. Teng, S. Wang*, L. Teng*, B. Kim*, Z. Yang*, W. Jiang*. Adaptive design of mRNA-loaded extracellular vesicles for targeted immunotherapy of cancer. Nature Communications, 2023, 14(1):6610.（*通讯，影响因子16.6） 7. Y. You#, Y. Tian#, Z. Yang#, J. Shi, K. Kwak, Y. Tong, A. Estania, J. Cao, W. Hsu, Y. Liu, C. Chiang, B. Schrank, K. Huntoon, D. Lee, Z. Li, Y. Zhao, H. Zhang, T. Gallup, J. Ha, S. Dong, X. Li, Y. Wang, W. Lu, E. Bahrani, L. Lee, L. Teng, W. Jiang, F. Lan, B. Kim, A. Lee. Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy. Nature Biomedical Engineering, 2023, 7(7):887-900.（ESI高被引,影响因子28.1） 8. Q. Zhu, Y. Zhang, M. Li, Y. Zhang, H. Zhang, J. Chen, Z. Liu, P. Yuan, Z. Yang*, X. Wang*. MiR-124-3p impedes the metastasis of non-small cell lung cancer via extracellular exosome transport and intracellular PI3K/AKT signaling. Biomarker Research, 2023, 11(1):1（*通讯，影响因子11.1） 9. S. Dong, Y. Bi, X. Sun, Y. Zhao, R. Sun, Y. Sun, Y. Wang, Z. Yang*, W. Jiang*, L. Teng*. Dual-loaded liposomes tagged with hyaluronic acid have synergistic effects in triple negative breast cancer. Small, 2022, e2107690.（*通讯，影响因子13.3） 10. Z. Huang#, B. Tang#, Y. Yang#, Z. Yang#, L. Shi, Y. Bai, B. Yan, R. Karnes, J. Zhang, R. Jimenez, L. Wang, Q. Wei, J. Yang, W. Xu, Z. Jia, H. Huang. MAP3K7-IKK Inflammatory Signaling Modulates AR Protein Degradation and Prostate Cancer Progression. Cancer Research, 2021, 81(17):4471-4484.（影响因子11.2） 11. Z. Yang#, J. Shi#, J. Xie, Y. Wang, J. Sun, T. Liu, Y. Zhao, X. Zhao, X. Wang, Y. Ma, V. Malkoc, C. Chiang, W. Deng, Y. Chen, Y. Fu, K. Kwak, Y. Fan, C. Kang, C. Yin, J. Rhee, P. Bertani, J. Otero, W. Lu, J. Yun, A. Lee, W. Jiang, L. Teng, B. Kim, L. Lee, Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation, Nature Biomedical Engineering, 2020, 4(1), 69-83.（封面论文，ESI高被引,影响因子28.1） 本课题组长期招聘博士后，欢迎优秀学者加入！ |
